REGULATION OF PROTEIN METABOLISM - M. Salinas and J. Burda.- CELL ADHESION MOLECULES OF THE IMMUNOGLOBULIN SUPERFAMILY IN THE NERVOUS SYSTEM - P. S. Walmod, M. V. Pedersen, V. Berezin, and E. Bock.- NEUROSECRETORY PROTEIN TRAFFICKING AND DENSE-CORE GRANULE BIOGENESIS IN NEUROENDOCRINE CELLS - T. Kim, M. Gondré-Lewis, I. Arnaoutova, N. Cawley, Y. Peng Loh.- PROTEIN SYNTHESIS AT SYNAPTIC SITES ON DENDRITES - O. Steward.- EMERGING FUNCTIONS OF THE CA2+ BUFFERS PARVALBUMIN, CALBINDIN D-28k AND CALRETININ IN THE BRAIN - B. Schwaller.- ACTIN, ACTIN-BINDING PROTEINS AND MYOSINS IN NERVOUS SYSTEM - R. Ishikawa.- TRANSGLUTAMINASE - A. J. L. Cooper, S.-Y. Kim.- PROTEIN ALTERATION IN MENTAL RETARDATION - M. A. Junaid, W. T. Brown.- PROTEIN SULFATION - S. Hemmerich.- PROTEIN FOLDING - A. Szilágyi, J. Kardos, S. Osváth, L. Barna, and P. Závodszky.- NEURODEGENERATIVE DEMENTIAS INVOLVING ABERRANT PROTEIN AGGREGATION - T. Kudo and M. Takeda.- POLYGLUTAMINE DISEASES - H. Okazawa.- THE PROTEASOME, PROTEIN AGGREGATION, AND NEURODEGENERATION - S. Wilk.- SERINE PROTEASES - J. Tóth, P. Medveczky, L. Szilágyi, and L. Gráf.- CALPAIN AS A TARGET FOR PREVENTION OF NEURONAL DEATH IN INJURIES AND DISEASES OF THE CENTRAL NERVOUS SYSTEM - S. K. Ray, M. K. Guyton, E. A. Sribnick, and N. L. Banik.- SECRETASE PROCESSING OF AMYLOID PRECURSOR PROTEIN (APP) AND NEURODEGENERATION (APP) - N. Marks and M. J. Berg.- THE BIOLOGY OF CASPASES IN CENTRAL NERVOUS SYSTEM TRAUMA - M. L. McEwen, J. E. Springer.- MICROGLIAL PROTEASES - H. Nakanishi.- MMPs AND OTHER MATRIX-DEGRADING METALLOPROTEINASES IN NEUROLOGICAL DISEASE - P. E. Gottschall and K. Conant.- PROTEASE INHIBITORS AND THEIR INVOLVEMENT IN NEUROLOGICAL DISORDERS - B. Tizon and E. Levy.- NEUROPEPTIDASES - K.-S. Hui.- UBIQUITINATION AND PROTEASOMAL PROTEIN DEGRADATION IN NEURONS - L. Klimaschewski.- PROTEASE ACTIVITY IN THE AGING BRAIN - D. A. Gray.- FROM CONCEPT TO POTENTIAL THERAPEUTICS: NEUROPROTECTIVE PEPTIDES - I. Gozes and J. Tiong Preface v Contributors ix Regulation of Protein Metabolism 1(34) M. Salinas J. Burda Cell Adhesion Molecules of the Immunoglobulin Superfamily in the Nervous System 35(118) P. S. Walmod M. V. Pedersen V. Berezin E. Bock Neurosecretory Protein Trafficking and Dense-Core Granule Biogenesis in Neuroendocrine Cells 153(16) T. Kim M. Gondre-Lewis I. Arnaoutova N. Cawley Y. Peng Loh Protein Synthesis at Synaptic Sites on Dendrites 169(28) O. Steward Emerging Functions of the ``Ca2+ Buffers'' Parvalbumin, Calbindin D-28k and Calretinin in the Brain 197(26) B. Schwaller Actin, Actin-binding Proteins and Myosins in Nervous System 223(20) R. Ishikawa Transglutaminase 243(16) A. J. L. Cooper S.-Y. Kim Protein Alterations in Mental Retardation 259(24) M. A. Junaid W. T. Brown Protein Sulfation 283(20) S. Hemmerich Protein Folding 303(42) A. Szilagyi J. Kardos S. Osvath L. Barna P. Zavodszky Neurodegenerative Dementias Involving Aberrant Protein Aggregation 345(10) T. Kudo M. Takeda Polyglutamine Diseases 355(16) H. Okazawa The Proteasome, Protein Aggregation, and Neurodegeneration 371(38) S. Wilk Serine Proteases 409(36) J. Toth P. Medveczky L. Szilagyi L. Graf Calpain as a Target for Prevention of Neuronal Death in Injuries and Diseases of the Central Nervous System 445(24) S. K. Ray M. K. Guyton E. A. Sribnick N. L. Banik Secretase Processing of Amyloid Precursor Protein (APP) and Neurodegeneration 469(46) N. Marks M. J. Berg The Biology of Caspases in Central Nervous System Trauma 515(36) M. L. McEwen J. E. Springer Microglial Proteases 551(14) H. Nakanishi MMPs and Other Matrix-Degrading Metalloproteinases in Neurological Disease 565(26) P. E. Gottschall K. Conant Protease Inhibitors and their Involvement in Neurological Disorders 591(34) B. Tizon E. Levy Neuropeptidases 625(28) K.-S. Hui Ubiquitination and Proteasomal Protein Degradation in Neurons 653(10) L. Klimaschewski Protease Activity in the Aging Brain 663(10) D. A. Gray From Concept to Potential Therapeutics: Neuroprotective Peptides 673(16) I. Gozes J. Tiong Index 689