Clinical Biochemistry Lecture Notes presents the fundamental science behind common biochemical investigations used in clinical practice. Taking a system-based approach, it explores the underlying physiological rationale for tests, with each test explained within the context of disruption by disease. Clinical Biochemistry Lecture Notes presents the fundamental science behind common biochemical investigations used in clinical practice. Taking a system-based approach, it explores the underlying physiological rationale for tests, with each test explained within the context of disruption by disease. Preface List of abbreviations About the companion website Chapter 1 Requesting and interpreting tests Chapter 2 Disturbances of water, sodium and potassium balance Chapter 3 Acid base balance and oxygen transport Chapter 4 Renal disease Chapter 5 Disorders of calcium, phosphate and magnesium metabolism Chapter 6 Diabetes mellitus and hypoglycaemia Chapter 7 Disorders of the hypothalamus and pituitary Chapter 8 Abnormalities of thyroid function Chapter 9 Disorders of the adrenal cortex and medulla Chapter 10 Investigation of gonadal function infertility, menstrual irregularities and hirsutism Chapter 11 Pregnancy and antenatal screening Chapter 12 Cardiovascular disorders Chapter 13 Liver disease Chapter 14 Gastrointestinal tract disease Chapter 15 Nutrition Chapter 16 Trauma, inflammation and immunity Chapter 17 Malignancy and tumour markers Chapter 18 Disorders of iron and porphyrin metabolism Chapter 19 Uric acid, gout and purine metabolism Chapter 20 Central nervous system and cerebrospinal fluid Chapter 21 Therapeutic drug monitoring and chemical toxicology Chapter 22 Clinical biochemistry in paediatrics and the elderly Index