Asymmetric Synthesis Of 3, 3-disubstituted Oxindoles

Dalpozzo, Renato (Univ Of Calabria, Pellissier, Helene (Aix-marseille Univ, Chimni, Swapandeep Singh (Guru Nanak Dev Univ, Rios Torres, Ramon (Univ Of Southampton

Omschrijving

Indole derivatives are the most common heterocycle compounds present in nature, for this reason, they have been referred to as "privileged structures". In fact, many approved drugs - and natural products - belong to this family. Among indole derivatives, oxindoles have a structural complexity, which have stimulated generations of synthetic chemists to design strategies for assembling these structures, and their enantioselective synthesis is still growing. This book proposes to describe the known enantioselective syntheses of oxindole derivatives. It is divided in six chapters each referring to a specific class of asymmetric oxindole derivatives. After the introduction, Chapter 2 describes all-carbon spirooxindoles; Chapter 3, open chain 3,3-dialkyloxindoles; Chapter 4, 3-substituted-3-aminooxindoles; Chapter 5, 3-substituted-3-hydroxyoxindoles; Chapter 6, 3-hetero-3-substituted oxindoles. It will be a useful tool for synthetic chemists, who assemble total synthesis of natural products, as well as for drug discovery chemists either in academic or in industry R&S laboratories.
Gratis verzending vanaf
€ 19,95 binnen Nederland
Jaar
2019
Taal
Engels
Pagina's
320
Gewicht
594 gr
EAN
9781786347299
Afmetingen
229 x 152 x 19 mm
Bindwijze
Hardback

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