The two volumes LNCS 4688 and LNBI 4689 constitute the refereed proceedings of the International Conference on Life System Modeling and Simulation, LSMS 2007, held in Shanghai, China, in September 2007. The 147 revised full papers were carefully reviewed and selected from 1383 submissions. The 63 papers of LNCS 4689 are organized in topical sections on modeling and simulation of societies and collective behavior, computational methods and intelligence in biomechanical systems, tissue engineering and clinical bioengineering, computational intelligence in bioinformatics and biometrics, brain stimulation, neural dynamics and neural interfacing, biological and biomedical data integration, mining and visualization, computational methods and intelligence in organism modeling and biochemical networks and regulation, computational methods and intelligence in modeling of molecular, cellular , multi-cellular behavior and design of synthetic biological systems, and others. The International Conference on Life System Modeling and Simulation (LSMS) was formed to bring together international researchers and practitioners in the field of life system modeling and simulation as well as life system-inspired theory and methodology. The concept of a life system is quite broad. It covers both micro and macro c- ponents ranging from cells, tissues and organs across to organisms and ecologic niches. These interact and evolve to produce an overall complex system whose beh- ior is difficult to comprehend and predict. The arrival of the 21st century has been marked by a resurgence of research interest both in arriving at a systems-level und- standing of biology and in applying such knowledge in complex real-world appli- tions. Consequently, computational methods and intelligence in systems, biology, as well as bio-inspired computational intelligence, have emerged as key drivers for new computational methods. For this reason papers dealing with theory, techniques and real-world applications relating to these two themes were especially solicited. Building on the success of a previous workshop in 2004, the 2007 International Conference on Life System Modeling and Simulation (LSMS 2007) was held in Shanghai, China, September 14¿17, 2007. The conference was jointly organized by The Shanghai University, Queen's University Belfast together with The Life System Modeling and Simulation Special Interest Committee of the Chinese Association for System Simulation. The First Section: Modeling and Simulation of Societies and Collective Behavior Phase Synchronization of Circadian Oscillators Induced by a Light-Dark Cycle and Extracellular Noise 1 Ying Li, Jianbao Zhang, and Zengrong Liu Detecting RNA Sequences Using Two-Stage SVM Classifier 8 Xiaoou Li and Kang Li Frequency Synchronization of a Set of Cells Coupled by Quorum Sensing 21 Jianbao Zhang, Zengrong Liu, Ying Li, and Luonan Chen A Stochastic Model for Prevention and Control of HIV/AIDS Transmission Dynamics 28 Min Xu, Yongsheng Ding, and Liangjian Hu Simulation of Artificial Life of Bee's Behaviors 38 Bin Wu, Hongying Zhang, and Xia Ni Hybrid Processing and Time-Frequency Analysis of ECG Signal 46 Ping Zhang, Chengyuan Tu, Xiaoyang Li, and Yanjun Zeng Robust Stability of Human Balance Keeping 58 Minrui Fei, Lisheng Wei, and Taicheng Yang Modelling Pervasive Environments Using Bespoke and Commercial Game-Based Simulators 67 Marc Davies, Vic Callaghan, and Liping Shen The Research of Artificial Animal's Behavior Memory Based on Cognition 78 Xiaojuan Ban, Shurong Ning, Jing Shi, and Dongmei Ai The Second Section: Computational Methods and Intelligence in Biomechanical Systems, Tissue Engineering and Clinical Bioengineering How to Ensure Safety Factors in the Development of Artificial Heart: Verified by the Usage of "Modeling and Simulation" Technology 88 Mitsuo Umezu Parametric-Expression-Based Construction of Interior Features for Tissue Engineering Scaffold with Defect Bone 97 Chunxiang Dai, Qingxi Hu, and Minglun Fang Computation of Uniaxial Modulus of the Normal and Degenerated Articular Cartilage Using Inhomogeneous Triphasic Model 104 Haijun Niu, Qing Wang, Yongping Zheng, Fang Pu, Yubo Fan, and Deyu Li Effect of the Plantar Ligaments Injury on the Longitudinal Arch Height of the Human Foot 111 Yunfeng Yang, Guangrong Yu, Wenxin Niu, Jiagian Zhou, Yanxi Chen, Feng Yuan, and Zuquan Ding Internet Living Broadcast of Medical Video Stream 120 Shejiao Li, Bo Li, and Fan Zhang Predicting Syndrome by NEI Specifications: A Comparison of Five Data Mining Algorithms in Coronary Heart Disease 129 Jianxin Chen, Guangcheng Xi, Yanwei Xing, Jing Chen, and Jie Wang Application of Image Processing and Finite Element Analysis in Bionic Scaffolds' Design Optimizing and Fabrication 136 Liulan Lin, Huicun Zhang, Yuan Yao, Aili Tong, Qingxi Hu, and Minglun Fang The Mechanical Properties of Bone Tissue Engineering Scaffold Fabricating Via Selective Laser Sintering 146 Liulan Lin, Aili Tong, Huicun Zhang, Qingxi Hu, and Minglun Fang The Third Section: Computational Intelligence in Bioinformatics and Biometrics Informational Structure of Agrobacterium Tumefaciens C58 Genome 153 Zhih,ua Liu and Xiao Sun Feature Extraction for Cancer Classification Using Kernel-Based Methods 162 Shutao Li and Chen Liao A New Hybrid Approach to Predict Subcellular Localization by Incorporating Protein Evolutionary Conservation Information 172 ShaoWu Zhang, YunLong Zhang, JunHui Li, HuiFeng Yang, YongMei Cheng, and GuoPing Zhou Support Vector Machine for Prediction of DNA-Binding Domains in Protein-DNA Complexes 180 Jiansheng Wu, Hongtao Wu, Hongde Liu, Haoyan Zhou, and Xiao Sun Feature Extraction for Mass Spectrometry Data 188 Yihui Liu An Improved Algorithm on Detecting Transcription and Translation Motif in Archaeal Genomic Sequences 197 Minghui Wu, Xian Chen, Fanwei Zhu, and Jing Ying Constructing Structural Alignment of RNA Sequences by Detecting and Assessing Conserved Stems 208 Xiaoyong Fang, Zhigang Luo, Bo Yuan, Zhenghua Wang, and Fan Ding Iris Verification Using Wavelet Moments and Neural Network 218 Zhiqiang Ma, Miao Qi, Haifeng Kang, Shuhua Wang, and Jun Kong Comprehensive Fuzzy Evaluation Model for Body Physical Exercise Risk 227 Yizhi Wu, Yongsheng Ding, and Hongan Xu The Fourth Section: Brain Stimulation, Neural Dynamics and Neural Interfacing The Effect of Map Information on Brain Activation During a Driving Task 236 Tao Shang, Shuoyu Wang, and Shengnan Zhang Worm 5: Pseudo-organics Computer and Natural Live System 246 Yick Kuen Lee and Ying Ying Lee Comparisons of Chemical Synapses and Gap Junctions in the Stochastic Dynamics of Coupled Neurons 254 Jiang Wang, Xiumin Li, and Dong Feng Distinguish Different Acupuncture Manipulations by Using Idea of ISI 264 Jiang Wang, Wenjie Si, Limei Zhong, and Feng Dong The Study on Internet-Based Face Recognition System Using PCA and MMD 274 Jong-Min Kim Simulation of Virtual Human's Mental State in Behavior Animation 284 Zhen Liu Hemodynamic Analysis of Cerebral Aneurysm and Stenosed Carotid Bifurcation Using Computational Fluid Dynamics Technique 292 Yi Qian, Tetsuji Harada, Koichi Fukui, Mitsuo Umezu, Hiroyuki Takao, and Yuichi Murayama Active/Inactive Emotional Switching for Thinking Chain Extraction by Type Matching from RAS 300 JeongYon Shim Pattern Recognition for Brain-Computer Interfaces by Combining Support Vector Machine with Adaptive Genetic Algorithm 307 Banghua Yang, Shiwei Ma, and Zhihua Li The Fifth Section: Biological and Biomedical Data Integration, Mining and Visualization Improved Locally Linear Embedding by Cognitive Geometry 317 Guihua Wen, Lijun Jiang, and Jun Wen Predicting the Free Calcium Oxide Content on the Basis of Rough Sets, Neural Networks and Data Fusion 326 Yunxing Shu, Shiwei Yun, and Bo Ge Classification of Single Trial EEG Based on Cloud Model for Brain-Computer Interfaces 335 Shaobin Li and Chenxi Shao The Modified Self-organizing Fuzzy Neural Network Model for Adaptability Evaluation 344 Zuohua Miao, Hong Xu, and Xianhua Wang Predicting Functional Protein-Protein Interactions Based on Computational Methods 354 Luwen Zhang and Wu Zhang The Chaos Model Analysis Based on Time-Varying Fractal Dimension 364 Jianrong Hou, Dan Huang, and Hui Zhao Bi-hierarchy Medical Image Registration Based on Steerable Pyramid Transform 370 Xiuying Wang and David Feng The Sixth Section: Computational Methods and Intelligence in Organism Modeling and Biochemical Networks and Regulation A Multiagent Quantum Evolutionary Algorithm for Global Numerical Optimization 380 Chaoyong Qin, Jianguo Zheng, and Jiyu Lai Developing and Optimizing a Finite Element Model of Phalange Using CT Images 390 Qingxi Hu, Quan Zhang, and Yuan Yao Reverse Engineering Methodology in Broken Skull Surface Model Reconstruction 399 Luyue Ju, Gaojian Zhong, and Xia Liu Identification and Application of Nonlinear Rheological Characteristics of Oilseed Based on Artificial Neural Networks 406 Xiao Zheng, Guoxiang Lin, Dongping He, Jingzhou Wang, and Yan You Prediction of Death Rate of Breast Cancer Induced from Average Microelement Absorption with Neural Network 414 Shouju Li, Jizhe Wang, Yingxi Liu, and Xiuzhen Sun An Adaptive Classifier Based on Artificial Immune Network 422 Zhiguo Li, Jiang Zhong, Yong Feng, and ZhongFu Wu Investigation of a Hydrodynamic Performance of a Ventricular Assist Device After Its Long-Term Use in Clinical Application 429 Yuma Kokuzawa, Tomohiro Shima, Masateru Furusato, Kazuhiko Ito, Takashi Tanaka, Toshihiro Igarashi, Tomohiro Nishinaka, Kiyotaka Iwasaki, and Mitsuo Umezu The Seventh Section: Computational Methods and Intelligence in Modeling of Molecular, Cellular, Multi-cellular Behavior and Design of Synthetic Biological Systems QSAR and Molecular Docking Study of a Series of Combretastatin Analogues Tubulin Inhibitors 436 Yubin Ji, Ran Tian, and Wenhan Lin A Software Method to Model and Fabricate the Defective Bone Repair Bioscaffold Using in Tissue Engineering 445 Qingxi Hu, Hongfei Yang, and Yuan Yao Using Qualitative Technology for Modeling the Process of Virus Infection 453 Hailin Feng and Chenxi Shao AOC-by-Self-discovery Modeling and Simulation for HIV 462 Chunxiao Zhao, Ning Zhong, and Ying Hao A Simulation Study on the Encoding Mechanism of Retinal Ganglion Cell 470 Chao-Feng Cai, Pei-Ji Liang, and Pu-Ming Zhang Modelling the MAPK Signalling Pathway Using a Two-Stage Identification Algorithm 480 Padhraig Gormley, Kang Li, and George W. Irwin The Eighth Section: Others Design and Path Planning for a Remote-Brained Service Robot 492 Shigang Cui, Xuelian Xu, Zhengguang Lian, Li Zhao, and Zhigang Bing Adaptive Fuzzy Sliding Mode Control of the Model of Aneurysms of the Circle of Willis 501 Peijun Ju, Guocai Liu, Li Tian, and Wei Zhang Particle Swarm Optimization Applied to Image Vector Quantization 507 Xubing Zhang, Zequn Guan, and Tianhong Gan Face Detection Based on BPNN and Wavelet Invariant Moment in Video Surveillance 516 Hongji Lin and Zhengchun Ye Efficient Topological Reconstruction for Medical Model Based on Mesh Simplification 526 Chunxiang Dai, Ying Jiang, Qingxi Hu, Yuan Yao, and Hongfei Yang Repetitive Motion Planning of Redundant Robots Based on LVI-Based Primal-Dual Neural Network and PUMA560 Example 536 Yunong Zhang, Xuanjiao Lv, Zhonghua Li, and Zhi Yang Tensile Test to Ensure a Safety of Cannula Connection in Clinical Ventricular Assist Device (VAD) 546 Takashi Tanaka, Tomohiro Shima, Masateru Furusato, Yuma Kokuzawa, Kazuhiko Ito, Kiyotaka Iwasaki, Yi Qian, and Mitsuo Umezu A Reproduction of Inflow Restriction in the Mock Circulatory System to Evaluate a Hydrodynamic Performance of a Ventricular Assist Device in Practical Conditions 553 Masateru Furusato, Tomohiro Shima, Yuma Kokuzawa, Kazuhiko Ito, Takashi Tanaka, Kiyotaka Iwasaki, Yi Qian, Mitsuo Umezu, ZhiKun Yan, and Ling Zhu Author Index 559