This volume contains the Proceedings of the 3nd International Symposium on Intelligent Interactive Multimedia Systems and Services (KES-IIMSS 2010). This third edition of the KES-IIMSS Symposium was jointly organized by the Department of Informatics of the University of Piraeus, Greece and the Department of Information Technologies of the University of Milan, Italy in conjunction KES International. KES International (KES) is a worldwide organisation that provides a professional community and association for researchers, originally in the discipline of Kno- edge Based and Intelligent Engineering Systems, but now extending into other related areas. Through this, KES provides its members with opportunities for publication and beneficial interaction. The focus of KES is research and technology transfer in the area of Intelligent Systems, i.e. computer-based software systems that operate in a manner analogous to the human brain, in order to perform advanced tasks. Recently KES has started to extend its area of interest to encompass the contribution that intelligent systems can make to sustainability and renewable energy, and also the knowledge transfer, innovation and enterprise agenda. Involving several thousand researchers, managers and engineers drawn from universities and companies world-wide, KES is in an excellent position to faci- tate international research co-operation and generate synergy in the area of arti- cial intelligence applied to real-world ¿Smart¿ systems and the underlying related theory. The KES annual conference covers a broad spectrum of intelligent systems t- ics and attracts several hundred delegates from a range of countries round the world. KES also organises symposia on specific technical topics, for example, Agent and Multi Agent Systems, Intelligent Decision Technologies, Intelligent Interactive Multimedia Systems and Services, Sustainability in Energy and Bui- ings and Innovations through Knowledge Transfer. KES is responsible for two peer-reviewed journals, the International Journal of Knowledge based and Intel- gent Engineering Systems, and Intelligent Decision Technologies: an International Journal.