Name: Metabolic engineering of Basfia succiniciproducens for the production of carbon-three compounds (Band 7) - Fabarius, Jonathan Thomas
Price: 59.6 EUR
Author: Fabarius, Jonathan Thomas
ISBN: 9783736999138

Metabolic engineering of Basfia succiniciproducens for the production of carbon-three compounds (Band 7)

Fabarius, Jonathan Thomas

Omschrijving

Beschreibung The recent rise of bio-succinic acid as an industrial platform chemical has brought the rumen bacterium Basfia succiniciproducens, a natural producer of this organic acid, into the focus of research. This work investigated the potential of B. succiniciproducens for the production of carbon-three chemicals from sugars. Beside the optimization of improved genetic tools, the C3 chemicals alanine, ¿-alanine and 3-hydroxypropionate (3-HP) were targeted. A new alanine producer, B. succiniciproducens ALA-1, exhibited good performance in the bioprocess. The next step demonstrated the proof-of-concept for ¿-alanine synthesis using the heterologous expression of aspartate 1 decarboxylase genes from Corynebacterium glutamicum or Vibrio natriegens. The expression of two additional genes enabled the de novo synthesis of up to 100 mg L-1 3-HP from glucose.

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Schrijver: Fabarius, Jonathan Thomas
Titel: Metabolic engineering of Basfia succiniciproducens for the production of carbon-three compounds (Band 7)
Uitgever: Cuvillier

Jaar: 2018
Taal: Engels
Pagina's: 144
Gewicht: 203 gr

EAN: 9783736999138
Afmetingen: 211 x 149 x 10 mm
Bindwijze: Paperback

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Metabolic engineering of Basfia succiniciproducens for the production of carbon-three compounds (Band 7)

Fabarius, Jonathan Thomas

Omschrijving

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