The role of the clinical pharmacist has evolved significantly in recent years, with California leading the way by establishing the first Advanced Practice Pharmacist (APh) separate license in 2017 through Bill SB493. This initiative has paved the path for pharmacists to assume expanded responsibilities and become integral members of primary care teams. In 2020, Wynn Medical Center embarked on a groundbreaking collaboration with the University of Southern California and 986 Pharmacy to establish a pioneering APh residency program aimed at training PharmD residents to become fully-fledged healthcare providers within a physician clinic setting. This comprehensive guide is designed to equip Advanced Practice Pharmacists and APh residents with a foundation of 350 common conditions encountered in primary care. Spanning across 24 chapters, this book addresses the APh profession, major disorders in internal medicine, common disorders in pregnancy and pediatrics, post-surgical and wound care, laboratory, imaging, biostatistics, and preventive measures. I extend my heartfelt gratitude to a dedicated team of international expert reviewers, editors, and students who have contributed their time, expertise, and insights to the creation of this textbook. Huynh Wynn Tran, MD, FACP, FACR Assistant Professor of Medicine, Rheumatology/Dermatology, and Pharmacy Founder/CEO of Wynn Medical Center Clinics, Los Angeles, USA